Table 3

Most important non-serious AEs of patients and HCPs

AEsProbability (%) for each specific AE to be ranked higher than the AE considered the least important by patients (ie, cold symptoms) (95% CI)
The six most important AEs for patients
 Insomnia95.9 (95.2 to 96.5)
 Anxiety95.2 (94.3 to 95.9)
 Fatigue94.6 (93.6 to 95.4)
 Weight gain93.2 (92.0 to 94.2)
 Agitation92.7 (91.5 to 93.8)
 Sexual dysfunction92.6 (91.4 to 93.8)
The six most important AEs for HCPs
 Sexual dysfunction99.2 (98.5 to 99.6)
 Weight gain98.9 (97.7 to 99.4)
 Erectile disorder98.8 (97.7 to 99.4)
 Sleepiness98.8 (97.6 to 99.4)
 Agitation98.4 (96.9 to 99.2)
 Nausea98.3 (96.6 to 99.2)
Additional AEs reported in the free-text responses by more than 5% of patients and HCPs who answered the open-ended questions (n=1323)Frequency (%)
Emotional numbing8.6
Trouble with concentration7.6
Irritability6
Withdrawal syndrome5.9
  • AE, adverse event; HCP, healthcare professional.