Table 1

Descriptive statistics

BaselineFirst assessmentImaging
%IIV meanIIV
SD
%IIV meanIIV
SD
%IIV meanIIV
SD
Panel A—Neuroticism EPQ-R Scale
‘Does your mood often go up and down?’
 Yes33%72.1853.3830%71.1047.0728%78.6454.66
 No67%72.3847.5470%73.0048.5072%74.9852.08
‘Do you ever feel just miserable for no reason?’
 Yes33%68.8946.5430%70.3441.6527%78.1351.82
 No67%74.0350.9070%73.3150.5473%75.2253.21
‘Are you an irritable person?’
 Yes25%72.8052.8724%73.4352.0622%72.7551.38
 No75%72.1548.3976%72.1146.7678%76.9653.23
‘Are your feelings easily hurt?’
 Yes48%75.4050.3746%73.5351.2843%75.1948.15
 No52%69.4048.6054%71.5045.1957%76.6456.13
‘Do you often feel fed-up?’
 Yes28%70.0847.6628%69.5346.2423%78.8753.15
 No72%73.1850.2372%73.5348.7277%75.1652.73
‘Would you call yourself a nervous person?’
 Yes18%77.8758.0617%72.9452.8415%76.4854.22
 No82%71.1147.4183%72.3247.0785%75.9352.60
‘Are you a worrier?’
 Yes45%71.8346.3946%73.8450.8542%74.8150.13
 No55%72.7151.9954%71.2445.6058%76.9154.75
‘Would you call yourself tense or highly strung?’
 Yes10%74.2548.1710%80.2860.568%74.9948.79
 No90%72.0949.7090%71.5746.4692%76.1153.20
‘Do you worry too long after an embarrassing experience?’
 Yes45%69.9140.6646%72.3651.0547%73.1247.35
 No55%74.2755.6654%72.4845.4053%78.5757.14
‘Do you suffer from nerves?’
 Yes16%75.1853.8714%71.0550.5812%67.8344.36
 No84%71.7848.6886%72.6547.6688%77.1053.77
‘Do you often feel lonely?’
 Yes12%73.6754.6112%70.2636.6711%74.4650.43
 No88%72.1248.8088%72.7349.4689%76.2153.13
‘Are you often troubled by feelings of guilt?’
 Yes23%68.9936.8622%73.6151.9924%76.8950.80
 No77%73.3352.7878%72.0846.8976%75.7453.47
Panel B—PHQ-2 Depression Scale
‘frequency of depressed mood’
 Not at all83%72.5351.2586%73.4749.3987%76.2953.42
 Several days15%71.7240.8512%65.3539.4811%72.9447.49
 More than half the days1%72.4543.131%79.2838.601%89.0460.27
 Nearly everyday1%60.7024.811%60.8828.681%54.5336.12
‘frequency of unenthusiasm/disinterest’
 Not at all87%71.9950.4189%72.9948.9290%76.3753.27
 Several days11%74.0743.299%70.4542.479%70.0547.67
 More than half the days1%65.7935.191%55.4825.831%89.5659.17
 Nearly everyday1%91.8853.721%58.1034.680%101.140.76
Panel C—other comorbid disorders
Heart attack
 Yes1%62.0433.941%75.1155.662%65.5251.29
 No99%72.4249.6699%72.3947.9798%76.2252.86
Angina
 Yes1%67.1534.691%72.8144.781%62.4727.99
 No99%72.3749.6799%72.4248.1299%76.1853.04
Stroke
 Yes1%79.4938.781%89.7351.711%71.7745.78
 No99%72.2649.6199%72.2348.0199%76.0652.90
High blood pressure
 Yes18%73.2543.8922%73.5153.5622%77.2148.83
 No82%72.1150.6778%72.1246.4378%75.6853.92
Diabetes
 Yes2%64.9123.102%69.5443.773%99.2951.22
 No98%72.4749.9298%72.5048.1897%75.3251.74
Panel D—covariates
Gender
 Male59%72.3248.2059%71.2848.0959%75.2254.45
 Female41%72.3151.3841%74.0548.0241%77.1450.48
Education
 College55%69.5045.2355%72.8448.9958%73.0451.96
 Other45%75.7754.1744%71.9246.9342%80.0653.77
BMI
 Normal weight41%73.1454.7442%74.0249.1545%77.9857.45
 Overweight44%73.1448.1942%73.2348.6940%74.4349.64
 Obese15%67.7236.9015%65.8142.6915%74.3246.10
Household Income
 <£18 00010%85.1774.4112%76.3142.5611%86.9065.49
 (£18 000, £30 999]23%76.4744.8226%74.2947.6327%79.0247.50
 (£31,000, £51 999]30%72.4247.1230%73.0850.6730%69.3845.53
 (£52 000, £100 000]28%68.7647.7523%73.6952.2123%79.3360.52
 >£100 00010%59.0335.009%55.6629.509%68.1649.72
Smoking status
 No95%72.8550.2096%72.2848.2497%75.8652.53
 Yes5%62.7734.294%76.2043.393%81.2562.33
Employment status
 Employed67%68.3345.7951%68.4846.1042%73.0249.65
 Other33%80.4855.6049%76.6049.7558%78.2254.98
Ethnicity
 White98%72.3749.4498%72.4247.6498%75.6252.47
 Other2%69.3255.052%72.6668.222%94.8466.43
Vegetable and fruit intake
 ≥5 unit per day76%72.3949.4774%72.7247.3979%75.3050.92
 <5 unit per day24%72.0649.7626%71.5949.9921%78.6459.32
Mean
Age566063
Alcohol consumption (g/day)18.3316.3916.37
  • BMI, body mass index; EPQ-R, Eysenck Personality Questionnaire-Revised; IIV, intraindividual variability; PHQ, Patient Health Questionnaire.