Stimulants v placebo for aggression related behaviours in attention deficit hyperactivity disorder at 1–42 days*

OutcomesNumber of studies (n)Mean effect size (95% CI)Percentage of patients with worse outcome†
*CI defined in glossary.
†Percentage of patients in the control group with a worse outcome than the average patient in the treatment group; see glossary.
Overt aggression
    Clinician ratings18 (367)0.76 (0.63 to 0.88)78% (74 to 81)
    Parent ratings13 (381)0.78 (0.42 to 1.14)78% (66 to 87)
    Teacher ratings16 (414)1.06 (0.79 to 1.32)86% (79 to 91)
    Overall ratings28 (683)0.86 (0.70 to 1.02)81% (76 to 85)
Covert aggression
    Clinician ratings6 (100)0.83 (0.20 to 1.46)80% (58 to 93)
    Overall ratings7 (131)0.75 (0.21 to 1.29)77% (58 to 90)