Risk of Alzheimer's disease (AD) in parents of children with Down's syndrome

Risk factorRelative risk of AD (95% CI)
*Not statistically significant
Mothers giving birth at ≤35 years4.8 (2.1 to 11.2)
Mothers giving birth at >35 years1.8 (0.6 to 5.1)*
Fathers having a child at ≤35 years1.0 (0.3 to 3.2)*
Fathers having a child at >35 years1.2 (0.4 to 3.4)*