Sertraline v placebo for post-traumatic stress disorder

Outcomes at 12 weeksSertralinePlaceboRBI (95% CI)NNT (CI)
Response rate53%32%64% (16 to 135)5 (3 to 17)
Mean change from baseline
SertralinePlaceboDifference in mean change from baseline (CI)
†CAPS-2=Clinician Administered PTSD Scale, Part 2; IES=Impact of Event Scale. Other abbreviations defined in glossary; RBI, NNT, CI, and mean differences calculated from data in article.
‡Not significant.
CAPS-2 total score−33.0−23.29.8 (1.8 to 17.8)
IES total score−16.2−12.14.1 (−0.4 to 8.6)‡