Intravenous immunoglobulin (IVIG) or plasma exchange v placebo for obsessive compulsive disorder and tic disorder at 1 month

OutcomesPoints improvement in score from baseline (% change)
‡Not significant for comparison with placebo.
IVIG Plasma exchange Placebo
Obsessive compulsive symptoms12 (45%)13 (58%)0.9 (3%)
Tics1.3 (19%)‡10.7 (58%)1.3 (12%)
Anxiety2.1 (31%)3.0 (47%)0.2 (3%)
Depression1.4 (26%)2.3 (44%)−0.1 (2%)
Emotional lability1.8 (29%)2.2 (35%)−0.1 (2%)
Global function2.9 (33%)2.8 (35%)0 (0%)
Global severity1.3 (26%)1.8 (36%)0 (1%)