Depressive episode recurrence rates at 3 years for nortriptyline, interpersonal psychotherapy (IPT), and placebo*

ComparisonEvent ratesRRR (95% CI)NNT (CI)
*Abbreviations defined in glossary; RRR, NNT, and CI calculated from data in article.
Nortriptyline and IPT v placebo20% v 90%78% (56 to 90)1 (1 to 2)
Nortriptyline and IPT v IPT20% v 64%67% (33 to 87)2 (2 to 6)
Nortriptyline and IPT v nortriptyline20% v 43%53% (−7.3 to 81)Not significant
Nortriptyline v placebo43% v 90%52% (29 to 71)2 (2 to 4)
Nortriptyline v IPT43% v 64%33% (−12 to 61)Not significant
IPT v placebo64% v 90%29% (4.6 to 51)4 (2 to 30)