Pooled relative risks (RRs) for neonatal mortality associated with various type of maternal opiate use

Major type of opiate used during pregnancyPooled RR (95% CI)
*Not significant
Heroin use3.27 (0.95 to 9.60)*
Methadone1.75 (0.60 to 2.33)*
Heroin and methadone6.37 (2.57 to 14.68)
Any methadone (with or without heroin use)3.00 (1.50 to 5.88)
Any opiate2.55 (1.89 to 3.38)