Serotonin specific reuptake inhibitors (SSRIs) v tricyclics and heterocyclics combined and reference drugs†

OutcomesSSRIs weighted EERControl weighted CERRRR (95% CI)Weighted ARRNNT (CI)
†Abbreviations defined in glossary; RRR, ARR, NNT, and CI calculated from data in article.
Discontinuation (combined drugs)31%33%8% (3 to 14)2.4%42 (24 to 148)
Discontinuation (reference drugs)35%38%10% (3 to 16)3.1%32 (19 to 139)