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Cognitive behavioural therapy does not reduce overall episode recurrence in people with recurrent bipolar disorder

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Q Does cognitive behavioural therapy plus treatment as usual reduce episode recurrence rates in a clinically representative sample of people with recurrent bipolar disorder?


Embedded ImageDesign:

Multicentre randomised control trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

Single blinded (assessors blinded).

Embedded ImageFollow up period:

Eighteen months.

Embedded ImageSetting:

Five centres in the UK; time frame not stated.

Embedded ImagePatients:

253 people aged 18 and over with DSM-IV diagnosis of bipolar disorder, a DSM-IV defined history of ⩾2 episodes of mania, hypomania, major depressive disorder, or mixed affective disorder (with one episode occurring in the last year), and contact with mental health services in the last six months. Exclusions: rapid cycling disorder; bipolar disorder secondary to an organic cause; severe DSM-IV borderline personality disorder with suicidal thoughts/intent in …

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  • For correspondence: Professor Jan Scott, Department of Psychological Medicine, PO Box 96, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK; j.scott{at}

  • Source of funding: Medical Research Council (UK).