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Universal and targeted cognitive behavioural approaches do not reduce depression in young people at risk of depression

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Q Are universal or targeted cognitive behavioural interventions in young people at risk of depression effective?


Embedded ImageDesign:

Multicentre, stratified, cluster randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:


Embedded ImageFollow up period:

Twelve months.

Embedded ImageSetting:

Thirty four schools in Queensland and New South Wales, Australia; time period not stated.

Embedded ImagePatients:

2479 young people in Year 9 (mean age 14.3 years), including 521 young people at high risk of depression (combined score for the Children’s Depression Inventory (CDI) and the Center for Epidemiological Studies-Depression Scale (CES-D) in the highest 20%).

Embedded ImageIntervention:

Universal cognitive behavioural intervention (eight weekly 45–50 minute sessions), targeted cognitive behavioural intervention (eight weekly 90 minute sessions delivered only to young people at high risk of depression), universal …

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  • For correspondence: Jeanie K Sheffield, School of Psychology, University of Queensland, Brisbane, Queensland 4072, Australia; jeanie{at}

  • Sources of funding: not stated.