Vardenafil improves comorbid erectile dysfunction and mild depression

doi:10.1136/ebmh.9.3.77

Article Text

Therapeutics

Vardenafil improves comorbid erectile dysfunction and mild depression

http://dx.doi.org/10.1136/ebmh.9.3.77

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Rosen R, Shabsigh R, Berber M, et al. Efficacy and tolerability of vardenafil in men with mild depression and erectile dysfunction: the depression-related improvement with vardenafil for erectile response study. Am J Psychiatry 2006;163:79–87.OpenUrl CrossRef PubMed Web of Science

Q Does vardenafil improve erectile dysfunction and mild major depressive disorder in men with both disorders?

METHODS

Design:

Randomised controlled trial.

Allocation:

Not stated.

Blinding:

Double blind.

Follow up period:

12 weeks.

Setting:

44 centres in the USA, Canada, France, Spain and Italy; December 2002 to November 2003.

Patients:

280 men aged 18 and over with erectile dysfunction for longer than 6 months (National Institutes of Health criteria) and untreated depressive disorder (a score of 13–23 (later modified to 11–17) on the Hamilton Depression Rating Scale and >13 on Center …

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