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Therapeutics
Mirtazapine reduces social anxiety and improves quality of life in women with social phobia

http://dx.doi.org/10.1136/ebmh.9.3.75

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    Muehlbacher M, Nickel MK, Nickel C, et al. Mirtazapine treatment of social phobia in women—a randomized, double-blind, placebo-controlled study. J Clin Psychopharmacol 2005;25:580–3.OpenUrlCrossRefPubMedWeb of Science

    Q Does mirtazapine improve symptoms and quality of life in women with social phobia?

    METHODS

    Embedded ImageDesign:

    Randomised controlled trial.

    Embedded ImageAllocation:

    Concealed.

    Embedded ImageBlinding:

    Double blind.

    Embedded ImageFollow up period:

    10 weeks.

    Embedded ImageSetting:

    General population, Germany; September to December 2004.

    Embedded ImagePatients:

    66 women with social phobia (DSM-IV). Exclusions: <18 years old; psychosis; severe major depressive episode; pregnancy; not using contraception; psychotherapy; suicidal; abusing drugs or alcohol; other illness; or current use of mirtazapine or other psychotropics.

    Embedded ImageIntervention:

    Mirtazapine (30 mg/day); placebo.

    Embedded ImageOutcomes:

    Social anxiety (Social Phobia Inventory (SPIN); Liebowitz Social …

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    Footnotes

    • For correspondence: Dr Marius Nickel, Inntalklinik, 84359 Simbach am Inn, Germany; m.nickel{at}inntalklinik.de

    • Source of funding: Not stated.