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Retrospective cohort study.
Medical Expenditure Panel Survey (MEPS), USA, a national sample of the civilian population; 1996 to 2001.
829 people aged 18 and over who had initiated antidepressant treatment for depression (DSM-IV or ICD-9) during the survey period. Exclusions: use of mood stabilising medications.
Discontinuation of antidepressant treatment.
Follow up period:
Of adults treated with antidepressants, 42.4% discontinued medication within the first 30 days, and a further 30% discontinued medication within 31–90 days of starting treatment. …
For correspondence: Dr M Olfson, New York State Psychiatric Institute/Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA;
Source of funding: Wyeth Research.
Please see http://www.ebmentalhealth.com/supplemental for additional commentary by Dr Michad Thase.
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