Article Text

Download PDFPDF
Combination treatment of behaviour therapy and medication significantly reduces obsessive-compulsive symptoms in people who have responded to pharmacotherapy

Statistics from

OpenUrlCrossRefPubMedWeb of Science

Q Does the addition of behaviour therapy to continuing medication benefit people with obsessive-compulsive disorder who have responded to drug treatment?


Embedded ImageDesign:

Randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

Single blinded.

Embedded ImageFollow up period:

Twelve months.

Embedded ImageSetting:

University Medical Centre Utrecht, the Netherlands; October 1998 to June 2002.

Embedded ImagePatients:

Ninety six adult outpatients with DSM-IV obsessive-compulsive disorder (OCD) who had responded to three months of medication (⩾25% reduction in score on Yale-Brown Obsessive Compulsive Scale (Y-BOCS)) with venlafaxine (300 mg/day) or paroxetine (60 mg/day). Exclusion criteria: comorbid Axis I disorder during past six months; Hamilton Rating Scale for Depression score >16; and cognitive and/or …

View Full Text


  • For correspondence: Nienke H Tenneij, PhD, Vrije Universiteit Amsterdam, Developmental Psychology, Van der Boechorststraat, 11081 BT Amsterdam, the Netherlands; nh.tenneij{at}

  • Sources of funding: GlaxoSmithKline and Wyeth Pharmaceuticals, the Netherlands.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.