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Atomoxetine improves teacher rated symptoms in children with ADHD more than placebo

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Q Is once-daily atomoxetine more effective than placebo at reducing attention deficit hyperactivity disorder (ADHD) symptoms displayed at school?


Embedded ImageDesign:

Multicentre randomised controlled trial.

Embedded ImageAllocation:


Embedded ImageBlinding:

Double blind.

Embedded ImageFollow up period:

Seven weeks.

Embedded ImageSetting:

Eight sites in the USA, two in Canada, and one in Puerto Rico.

Embedded ImagePatients:

153 children aged 8–12 years with ADHD (DSM-IV); with symptom severity on the investigator administered ADHD Rating Scale-IV-Teacher Version (ADHDRS-IV-Teacher:Inv) at least 1.0 standard deviation (SD) above age and gender norms, and at least 1.5 SD above norms on …

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  • For correspondence: Dr A J Allen, Lilly Corporate Center, Indianapolis, IN 46285, USA; allenaj{at}

  • Sources of funding: Eli Lilly and Company.