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Randomised controlled trial.
Follow up period:
Five universities, USA; time period not stated.
101 children and adolescents aged 12–17 years with autism and impairing behavioural symptoms (DSM-IV, Autism Diagnostic Interview (revised); mean age 8.8 years; 82% male). Exclusions: not stated.
Risperidone (0.5 to 3.5 mg/day); placebo.
Symptomatic behaviours (modified parent rated Ritvo-Freeman …
For correspondence: Dr C J McDougle, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202-4800, USA;
Sources of funding: National Institute of Health, USA.
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