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Pharmacotherapy and cognitive behavioural therapy: similarly cost effective compared with community referral for disadvantaged women with major depression

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Q What is the relative cost effectiveness of pharmacotherapy, cognitive behavioural therapy, and community referral for low income minority women with major depression?


Embedded ImageDesign:

Randomised controlled trial.

Embedded ImageAllocation:

Not stated.

Embedded ImageBlinding:

Not stated.

Embedded ImageFollow up period:

Twelve months.

Embedded ImageSetting:

Family planning clinics and paediatric related services in four US counties.

Embedded ImagePatients:

267 low income minority women with major depression on Composite International Diagnostic Interview. Exclusions: bereavement; substance abuse; pregnancy; breastfeeding, or currently receiving mental health care.

Embedded ImageIntervention:

Pharmacotherapy (paroxetine hydrochloride or bupropion hydrochloride for up to six months); …

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  • For correspondence: Dennis A Revicki, PhD, Center for Health Outcomes Research, MEDTAP Institute, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA; Dennis.Revicki{at}

  • Sources of funding: National Institute of Mental Health and GlaxoSmithKline.

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