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Randomised controlled trial.
Follow up period:
Outpatients recruited by advertisements in local newspapers in the US.
Forty people aged 18–65 years with DSM-IV diagnoses of pathological gambling and bipolar spectrum disorder (bipolar II, bipolar disorder not otherwise specified, or cyclothymia). People with bipolar I disorder or major medical illness were excluded from the trial.
Lithium: dose titration 300 mg/day for 4 days, 300 mg twice daily for 4 days, 300 mg three times daily …
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