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Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam

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Q Is lorazepam an effective alternative to haloperidol-promethazine for rapid tranquilisation of violent or agitated psychiatric patients?

METHODS

Embedded ImageDesign:

Randomised controlled trial.

Embedded ImageAllocation:

Not reported.

Embedded ImageBlinding:

Assessors for primary outcome were blind to treatment allocation. Other assessors were unblinded.

Embedded ImageFollow up period:

Four hours.

Embedded ImageSetting:

Psychiatric emergency services at a medical college in Vellore in Tamil Nadu, India in 2002.

Embedded ImagePatients:

200 people with disruptive behaviour requiring intramuscular sedation at presentation to emergency psychiatric services. People at risk of complication from either treatment were excluded. …

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