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PTSD plus depression are comorbid conditions but depression can occur independently in the acute aftermath of trauma

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Q Following trauma, are depression and post-traumatic stress disorder separate conditions, or are they a single traumatic stress construct?


Embedded ImageDesign:

Prospective longitudinal study.

Embedded ImageSetting:

Victoria, Australia; timeframe not stated.

Embedded ImagePopulation:

363 people aged 18–70 years admitted to a level 1 trauma service with injuries requiring hospital stays of >1 day who were stable and without pain. Exclusions included severe brain injury or recent opioid analgesia.

Embedded ImageAssessment:

The relations between post-traumatic stress disorder (PTSD), depression, and predictor variables were examined using canonical correlations and multinomial logistic regression.

Embedded ImageOutcomes:

PTSD was assessed with the Clinician-Administered PTSD Scale (DSM-IV). Participants were subsyndromal if they met re-experiencing symptoms and either avoidance or arousal symptoms criteria. Depression and minor depression were diagnosed with the Structured Clinical Interview (DSM-IV). People …

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