Article Text

Download PDFPDF

Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder

Statistics from Altmetric.com

OpenUrlCrossRefPubMedWeb of Science

Q What are the effects of lamotrigine and lithium for maintenance treatment in recently depressed people with bipolar I disorder?

METHODS

Embedded ImageDesign:

Randomised controlled trial.

Embedded ImageAllocation:

Unclear.

Embedded ImageBlinding:

Double blind.

Embedded ImageFollow up period:

18 months.

Embedded ImageSetting:

79 centres in 15 countries; 1997 to 2001.

Embedded ImagePatients:

463 adults with bipolar I disorder (mean age range 42 to 44 years), who were stabilised with lamotrigine during an 8–16 week open label phase (n = 966). Main inclusion criteria: current or recent (past 60 days) DSM-IV major depressive episode; ⩾1 manic or hypomanic episodes, and ⩾1 depressive episodes within 3 years of enrolment. Exclusions: >6 DSM-IV mood episodes in the past year; significant psychiatric or medical comorbidity; …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.