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Outreach supported antidepressant treatment and cognitive behavioural therapy are effective for depression in low income minority women

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Q What is the effect of guideline concordant care (ie antidepressant medication or cognitive behavioural therapy) compared with community care for depression in low income minority women?


Embedded Image  Design:

Randomised controlled trial.

Embedded Image  Allocation:


Embedded Image  Blinding:

Single blind (outcome assessors blinded).

Embedded Image  Follow up period:

Six months.

Embedded Image  Setting:

Four suburban county health and welfare services, Washington, DC, USA; March 1997 to May 2002.

Embedded Image  Patients:

267 low income women (117 black and 16 white women born in the USA, 134 Latina women born in Latin America) diagnosed with major depressive disorder using the Composite International Diagnostic Interview. Exclusions: bereavement, substance abuse, pregnancy or planning pregnancy in next 6 months, breast feeding, and current mental health care.

Embedded Image  Intervention:

Antidepressant medication for 6 months (paroxetine 10–50 mg per day, or buproprion for participants not tolerating paroxetine or …

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