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Review: sildenafil improves sexual and erectile function in men

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QUESTION: In men with erectile dysfunction (ED), is sildenafil effective for improving erectile or sexual function?

Data sources

Studies were identified by searching Medline, EMBASE/Excerpta Medica, the Cochrane Library, PsycLIT, the National Research Register, Pharmline, Science Citation Index, Premedline, and internet search engines in June 1999 using the terms sildenafil and Viagra. 8 journals were hand searched: BMJ, Lancet, JAMA New England Journal of Medicine, British Journal of General Practice, Drug, Inpharma, and Scrip. Reference lists of relevant studies and a Food and Drug Administration review were scanned. Pfizer Ltd and experts in the field were contacted.

Study selection

Published or unpublished randomised controlled trials …

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