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Review: evidence on anxiolytic drugs for smoking cessation is inconclusive

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QUESTION: Do drugs with anxiolytic properties help people to stop smoking?

Data sources

Studies were identified by searching Medline, EMBASE/Excerpta Medica, the Cochrane Tobacco Addiction Group's specialised register, and abstracts from the meetings of the Society for Research on Nicotine and Tobacco.

Study selection

Studies were selected if they were randomised trials comparing a drug with anxiolytic properties with placebo or an alternative treatment with a follow up ≥6 months. Studies on β blockers were included, whereas studies on clonidine were not (clonidine is covered in a separate Cochrane review*).

Data extraction

2 reviewers extracted data on participant characteristics, drug regimens, method of randomisation, completeness of follow up, and results; the outcome was abstinence from smoking assessed at ≥6 months of follow up. Reviewers rated the quality of study methods.

Main results

6 studies met …

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