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QUESTION: In adolescents with type 1 diabetes, how effective are behavioural interventions in improving management of diabetes?
Studies were identified by searching 11 databases to June 1999; handsearching the journals Diabetes Care, Diabetic Medicine, and Practical Diabetes International; contacting researchers in the field for published or unpublished work; and scanning reference lists for additional articles.
Studies were selected if they were empirical studies involving participants 9–21 years of age with type 1 diabetes, and the study reported an evaluation of a behavioural intervention (≥1 of education, skills training, or any other form of behavioural or psychosocial intervention designed to improve adolescents' diabetes management). The studies were also screened for randomised, non-randomised, or waiting list control group designs.
Data were extracted on study design, number of participants, type of intervention, and effects on outcomes. Effect sizes were calculated and outcomes were categorised as psychosocial (eg, self efficacy for diabetes management, measures of family climate or family conflict, diabetes specific stress, and quality of life), glycated haemoglobin (GHb), other metabolic measures, self management behaviours, and knowledge of diabetes.
35 studies had randomised, non-randomised, or waiting list control group designs, and involved a mean of 55 patients (mean age 12 y, mean duration of diabetes 5 y). 24 studies were randomised controlled trials; 16 trials evaluated 18 interventions with sufficient data to calculate effect sizes. An overall small to medium beneficial effect of behavioural interventions on adolescent diabetes management was seen when the mean effect sizes of all studies were pooled (the table⇓ shows the mean effect sizes for each outcome). Theoretically based interventions were more effective than those that were not.
In adolescents with type 1 diabetes, behavioural interventions have a small to medium beneficial effect on diabetes outcomes.
Clear evidence exists that strict control of blood sugars in patients with type 1 diabetes mellitus ameliorates the progression of microvascular complications. Psychosocial and behavioural factors have an important influence on the adequacy of metabolic control. Hampson et al reviewed the effectiveness of behavioural interventions for adolescents with type 1 diabetes. They found that the mean effect size for the interventions across all outcomes, and for GHb in particular, was 0.33, indicating a small to medium sized beneficial effect. This effect size for GHb improvement translates into a change of 0.6% in haemoglobin Alc, which is about one third of that found in the Diabetes Control and Complications Trial. It is encouraging that some benefit can be shown for interventions in this age group, but the persistence of the improvement and the extent to which it lowers the risk of complications remains to be determined.
This review showed that interventions with a theoretical foundation were more effective than other interventions, with the most effective involving family interventions, coping skills training, and problem solving related to diabetes management. However, the review does not discuss interventions for specific problems such as depression or eating disorders, both of which are common among adolescents with diabetes.1, 2 In fact, eating disorders in adolescents with diabetes have been associated with a three-fold increase in the risk of retinopathy.3
Although problem solving and skill training may be effective for a broad mix of patients, there is likely to be value in tailored interventions directed to alleviate specific disturbances. Further research is needed, however, to clarify the persistence of change and the health benefits associated with behavioural interventions in adolescents with type 1 diabetes.
Source of funding: UK National Health Service Health Technology Assessment Programme.
For correspondence: Dr S E Hampson, Department of Psychology, University of Surrey, Guildford, Surrey GU2 5XH, UK. Fax +44 (0)1483 879553.
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