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QUESTION: What evidence supports practice parameters for the surveillance, screening, and diagnosis of children with autism?
A panel of experts in autism was convened. Studies in all languages were identified by searching Medline and PsycINFO using the terms autistic, autism, and pervasive; books recommended by members of the panel were also reviewed.
Studies were selected if they were published since 1990, were review papers or meta-analyses developed for DSM-IV, or were included in the overview of the National Institutes of Health State of the Science Conference on Autism in 1995.
Studies were assessed for the strength of their evidence: Class I: prospective studies with a description of the study population, inclusion and exclusion criteria specified, adequate sample size; interpretations of evaluations done blinded to outcome; and a satisfactory description of …
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