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Randomised (allocation concealed*), unblinded*, controlled trial with 1 year of follow up.
A military medical referral centre in the US.
120 active duty military personnel (mean age 25 y, 94% men) admitted to hospital with a moderate to severe closed head injury manifested by a Glasgow Coma Scale score of ≤13, or post-traumatic amnesia of ≥24 hours, or focal cerebral contusion or haemorrhage. Other inclusion criteria included head injury within 3 months, Rancho Los Amigos cognitive level of 7 (oriented, appropriate), and no previous severe traumatic brain injury. …
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