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The Beck Depression Inventory had low sensitivity and moderate specificity for detecting depression in patients with Alzheimer's disease

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QUESTION: Is the Beck Depression Inventory (BDI) an appropriate screening tool for depression in patients with Alzheimer's disease (AD)?


Blinded comparison of the 21 item BDI (revised version) with ICD-9 and ICD-10 diagnosis of depression.


The neuropsychiatric (tertiary referral) clinics at Addenbrooke's Hospital, UK.


2 samples were studied: 129 patients with probable AD (AD based on NINCDS-ADRDA criteria, mean age 62 y, 64% men) and 52 with probable AD plus depression (mean age 62 y, 52% men).

Description of test and diagnostic standard

The BDI was self administered during a 45 minute computerised testing session. 8 core questionnaires were given during this session one of which was the …

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