Meta-analysis of rare events requires special considerations regarding which statistical method to use. This is because standard meta-analytical models are not well suited for the task, especially when some of the identified studies have reported zero events in one or more treatment groups.
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Contributors No other contributor.
Funding OE received funding from the Swiss National Science Foundation, grant number No. 180083.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Not required.
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