Article Text

Download PDFPDF

Developing digital interventions for people living with serious mental illness: perspectives from three mHealth studies
  1. Bruno Biagianti1,2,3,
  2. Diego Hidalgo-Mazzei4,
  3. Nicholas Meyer5
  1. 1 Department of Psychiatry, University of California at San Francisco, San Francisco, California, USA
  2. 2 Department of Health Sciences, University of Milan, Milan, Italy
  3. 3 Research and Development, Posit Science Inc., San Francisco, California, USA
  4. 4 Department of Psychiatry and Psychology, Bipolar Disorders Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain
  5. 5 Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK
  1. Correspondence to Dr Nicholas Meyer, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London SE5 8AF, UK; nicholas.meyer{at}


The rapidly expanding field of mobile health (mHealth) seeks to harness increasingly affordable and ubiquitous mobile digital technologies including smartphones, tablets, apps and wearable devices to enhance clinical care. Accumulating evidence suggests that mHealth interventions are increasingly being adopted and valued by people living with serious mental illnesses such as schizophrenia and bipolar disorder, as a means of better understanding and managing their condition. We draw on experiences from three geographically and methodologically distinct mHealth studies to provide a pragmatic overview of the key challenges and considerations relating to the process of developing digital interventions for this population.

  • Mental Health
  • Psychiatry

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See:

View Full Text

Statistics from


  • Contributors All authors contributed equally to the manuscript.

  • Funding NM is supported by a Medical Research Council Clinical Research Training Fellowship,MR/P001378/1. BB is supported by the National Institute of Mental Health Training Grant T32 and partially by Posit Science, a company with a commercial interest in the training software used in the CLIMB study. SIMPLe was supported by research grants from the Spanish Ministry of Economy and Competitiveness PI14/00286 and PI15/00588, Instituto de Salud Carlos III. DH-M is supported by a Rio Hortega grant (CM15/00127) from Instituto de Salud Carlos III.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.