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Review: incidence of dementia and Alzheimer's disease increases with increasing age

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Question Are incidence rates of dementia related to age, sex, and national differences?

Data sources

A search was done in Medline (1966–97) for incidence studies and the bibliographies of relevant articles were reviewed.

Study selection

Studies were selected if the case finding was based on a field survey or study of medical and social agencies, age specific incidence rates of dementia were reported for age groups spanning ≤10 years, the patient sample was population based, incidence rates were reported for mild or moderate dementia, and the SEs of the incidence rates were calculable.

Data extraction

Age specific incidence rates and SEs were extracted from each study. Other study features extracted were diagnosis (dementia, Alzheimer's disease, or vascular dementia), diagnostic criteria used (DSM-III-R, National Institute of Neurological and Cognitive Disorders and Stroke, or other), severity of dementia, study design, …

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