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Randomised, double blind, placebo controlled trial with 12 weeks follow up.
13 centres in the US and 1 centre in Canada.
187 patients ≥18 years of age (mean age 36 y, 57% women) with a DSM-IV diagnosis of generalised social phobia. Exclusion criteria included concurrent use of psychoactive medication, narcotic analgesics, warfarin sodium, digitalis glycosides, phenytoin, cimetidine or sulfonylurea derivatives; use of any psychotropic agent or β blockers within the previous 14 weeks; use of depot neuroleptics within the previous 12 weeks; clinically predominant Axis I diagnosis within the previous 6 months; substance abuse or substance dependence; and those considered to be serious …
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