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ABSTRACT FROM: Andersson NW, Gustafsson LN, Okkels N, et al. Depression and the risk of autoimmune disease: a nationally representative, prospective longitudinal study. Psychol Med 2015;45:3559–69.
What is already known on this topic
Autoimmune diseases are, according to a previous nationwide Danish register study, associated with a 57% increased subsequent risk of depression (45% after excluding the effect of infections).1 However, no large-scale study has previously investigated the longitudinal associations with autoimmune diseases after the depression diagnosis.
Methods of the study
Andersson et al investigated the longitudinal association between the date of a first-time hospital contact for depression and the subsequent risk of a first-time hospital contact for autoimmune diseases. The authors used the Danish nationwide registers with virtually complete follow-up of all hospital contacts with depression and autoimmune diseases. A total of 145 217 individuals with a hospital contact for depression were identified during the years 1995–2012, and each individual was match-controlled with six other individuals from the Danish population (resulting in a total study population of 1 016 519 individuals). During the study period, among the target …
Footnotes
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
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