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Routine use of antipsychotics to prevent or treat delirium is not recommended
  1. Taro Kishi
  1. Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan;

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ABSTRACT FROM: Neufeld KJ, Yue J, Robinson TN, et al. Antipsychotic medication for prevention and treatment of delirium in hospitalized adults: a systematic review and meta-analysis. J Am Geriatr Soc 2016;64:705–14.

What is already known on this topic

The American Geriatrics Society has developed guidelines to respond to the question of whether the use of antipsychotic medications in the perioperative period to prevent or treat delirium in older adults is supported by scientific evidence.1 ,2 Although the focus was on older adults after surgery, the panel raised concerns that the existing literature was too limited. Therefore, Neufeld et al conducted a systematic review and meta-analysis addressing two clinical questions: (1) does ‘preventive’ antipsychotic medication reduce the incidence of postoperative delirium in adult patients? (2) does antipsychotic treatment in hospitalised adult medical or surgical patients with delirium improve outcomes such as duration and severity of delirium?

Methods of the study

This systematic review included published and unpublished randomised …

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  • Competing interests TK has received speaker's honoraria from Abbvie, Astellas, Daiichi Sankyo, Dainippon Sumitomo, Eisai, Eli Lilly, GlaxoSmithKline, Janssen, Yoshitomi, Otsuka, Meiji, Mochida, Shionogi, Tanabe-Mitsubishi, Tsumura, Novartis and Pfizer and has a Fujita Health University School of Medicine research grant and Grant-in-Aid for Young Scientists (B).

  • Provenance and peer review Commissioned; internally peer reviewed.

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