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Support for the link between adolescent mental health problems and subsequent perinatal depression: a 20-year prospective cohort study
  1. Wendy Nilsen
  1. Correspondence to Domain for Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway; wendy.nilsen{at}

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ABSTRACT FROM: Patton GC, Romaniuk H, Spry E, et al. Prediction of perinatal depression from adolescence and before conception (VIHCS): 20-year prospective cohort study. Lancet 2015;386:875–83.

What is already known on this topic

Depression is one of the leading contributors to the global burden of disease,1 with an increased vulnerability for women during adolescence2 and the perinatal period.3 Although former studies indicate that perinatal depression has a unique profile without history of mental health disorders,4 there is a lack of studies that prospectively and robustly examine the link between mental health before conception and subsequent perinatal mental health.

Methods of the study

Patton and colleagues use the VIHCS (Victorian Intergenerational Health Cohort Study) in which 872 females from an adolescent cohort study initiated in August 1992 in the state of Victoria, Australia (The Victorian Adolescent Health Cohort Study …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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