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ABSTRACT FROM: Hjorthøj C, Østergaard ML, Benros ME, et al. Association between alcohol and substance use disorders and all-cause and cause-specific mortality in schizophrenia, bipolar disorder, and unipolar depression: a nationwide, prospective, register-based study. Lancet Psychiatry 2015;2:801–8.
What is already known on this topic
Excess mortality has been well described among people with severe mental illness (SMI) or substance use disorders (SUDs) in various settings.1 However, research about how SUDs impact mortality for people with SMI is scarce.2 To further address the issues on the potential contribution of SUDs on elevated mortality in people with SMI (defined as schizophrenia, bipolar disorder and unipolar depression), studies evaluating mortality in SMI cohorts in relation to SUDs are warranted.
Methods of the study
This cohort study was based on the nationwide Danish register systems with identified schizophrenia, bipolar disorder or unipolar depression patients and their demographics, diagnoses of SUDs, date and primary cause of death. A total of 41 470 patients with schizophrenia, 11 739 with bipolar …
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