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ABSTRACT FROM: Sharpe M, Walker J, Holm Hansen C, et al., SMaRT (Symptom Management Research Trials) Oncology-2 Team. Integrated collaborative care for comorbid major depression in patients with cancer (SMaRT Oncology-2): a multicentre randomised controlled effectiveness trial. Lancet 2014;384:1099–108.
What is already known on this topic
Several meta-analytic studies have now concluded that collaborative care interventions are effective in reducing symptoms of depression in the primary care setting.1 These interventions have been shown to be more cost-effective than face-to-face cognitive behavioural therapy (CBT) and pharmacological treatment.2 Collaborative care interventions are now beginning to be tested in patients with depression comorbid with chronic illnesses, including cancer.3
Methods of the study
The study was an RCT comparing the effectiveness of a collaborative care intervention with usual care (1:1 ratio) in 500 patients diagnosed with major depression from cancer clinics in Scotland, UK. The intervention was a manualised, multicomponent collaborative treatment delivered by oncology …
Competing interests None.
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