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Review: psychosocial mood management improves smoking cessation in people with current and past depression

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Question: How effective are smoking cessation interventions (SCI) with a mood-management component in people with current depression or past depression?

Outcomes: Smoking cessation for at least six consecutive months from quit date (preferably by biochemical validation; short lapses were permitted).


Design: Systematic review with meta-analysis.

Data sources: The Tobacco Addiction Group Specialised Register of Controlled trials (populated from searches of major databases including MEDLINE, EMBASE, PsycINFO, CENTRAL) was searched from inception to April 2013. This was supplemented by hand search of journals, conference proceedings and reference lists of identified studies and contact with experts.

Study selection and analysis: RCTs in adult smokers with current or past major depression or depressive symptoms (DSM-IV; Beck Depression Scale; Center for Epidemiologic Studies Depression or other defined scale) that compared pharmacological or psychosocial SCI with and without a mood-management component. Two reviewers rated study quality, assessed risk of bias and extracted data. Meta-analyses were performed …

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  • Sources of funding: STIVORO—for a smoke-free future, The Netherlands; Vrije Universiteit Amsterdam, The Netherlands; Trimbos-Instituut, Netherlands Institute of Mental Health and Addiction, The Netherlands.


  • Competing interests None.

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