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The DAISY psychosocial intervention does not improve outcomes in patients with mild Alzheimer's disease or their carers

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Question: What are the effects of a semitailored multicomponent intervention for patients with mild Alzheimer's disease and their carers?

Patients: In total, 330 patients with recently diagnosed mild Alzheimer's disease living in the community and their caregivers. Other inclusion criteria: age ≥50 years, DSM-IV dementia, probable Alzheimer's disease (National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria) or Lewy body dementia (McKeith criteria), diagnosis in past 12 months, mini-mental state examination (MMSE) score ≥20, primary caregiver willing to participate. Exclusions: Severe somatic or psychiatric comorbidity, participation in other intervention studies.

Setting: Primary care and memory clinics in five country districts in Denmark; time period not stated.

Intervention: Danish Alzheimer Study (DAISY) multicomponent intervention plus control support or control support alone over 12 months. DAISY consisted of counselling, information and support. Patients and their caregivers received up to seven counselling sessions (two for the patient and caregiver, two for the patient only, two for the …

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  • Sources of funding: National Board of Social Services at the Danish Ministry of Social Affairs, the Danish Ministry of Health and the Danish Heart Foundation.


  • Competing interests None.