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Lifetime nicotine dependence shows a cross-sectional association with lifetime incomplete suicide attempts

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What is the relationship between nicotine dependence and attempted suicide?


34 653 community-dwelling adults participating in a nationally representative survey (National Epidemiologic Survey on Alcohol and Related Conditions, NESARC). Data were collected by trained interviewers. 70.2% of participants had completed both waves of the study; those who did not complete both waves were omitted. Only data collected in the second wave of the study were analysed in the current study.


General population, USA; 2004–2005.


Further variables relating to tobacco use were also collected (age of first use, frequency and amount of use). Data on sociodemographic factors, DSM-IV mental disorders (AUDADIS-IV) and physical comorbidities were also collected, and the analyses were adjusted for these factors.


Suicide attempts, by self-report in response to a question regarding whether suicide had ever been attempted during the participant's life. Frequency and age at first and most recent attempt were also recorded.



Cross-sectional study.

Main results

Lifetime nicotine dependence was reported by 7557 participants (21.8%), past-year dependence by 4512 (13.0%) and prior to past-year dependence by 1842 …

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  • Sources of funding Manitoba Health Research Council, Canadian Institutes of Health Research.


  • Competing interests None

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