Statistics from Altmetric.com
Does a single annual vitamin D supplement have a beneficial effect on mental well-being, and are higher serum vitamin D levels associated with better mental well-being?
2317 women aged 70 or older with an identified risk factor for hip fracture (ie, maternal hip fracture, self-reported ‘faller’, fracture since age 50 and/or high risk of low vitamin D and osteoporosis. A group of 150 participants was selected for a substudy looking at the relationship between serum 25-hydroxyvitamin D levels and mental well-being. Exclusions: albumin-corrected calcium >2.65 mmol/l, vitamin D supplementation >400 IU/day, other bone health related parameters and inability to provide informed consent or data concerning falls/fractures.
Community setting, Melbourne, Australia; 2003–2008.
500 000 IU vitamin D3 annually during autumn/winter versus placebo. The dose was divided into 10 tablets and was taken orally on 1 day.
Mental well-being assessed using the General Mental Health Questionnaire (GHQ-12), the 12-item Short Form Health Survey (SF-12), the WHO Well-Being Index and Patient Global Impression–Improvement (PGI-I) scores. The GHQ-12 was administered to participants recruited after 2005 only and completed at …
Sources of funding Australian National Health and Medical Research Council, and the Government Department of Health and Ageing.
Competing interests None.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.