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Is cognitive remediation an effective treatment for schizophrenia?
Overall cognition, verbal and visual learning and memory, speed of processing, attention/vigilance, reasoning/problem solving and social cognition. Many different neuropsychological assessment tools were used for measurement of each cognitive domain.
Systematic review with meta-analysis.
MEDLINE and PsycINFO (search date not given) were searched for English language articles.
Study selection and analysis:
Randomised controlled trials examining psychosocial interventions aimed at improving cognitive function in people with schizophrenia, schizoaffective disorder, or schizophreniform disorder. Neuropsychological tests of general effects had to be included and were assigned to cognitive domains (described by the Measurement and Treatment Research to Improve Cognition in Schizophrenia) of verbal and non-verbal working memory, verbal and visual learning and memory, speed of processing, attention/vigilance, reasoning/problem solving and social cognition. Effect sizes were determined using post-treatment group means (and SD), ANCOVA, MANCOVA or pre-post difference scores. Fixed effect models were used in meta-analysis or random effects when there …
Source of funding: NIMH grant MH77210 and National Institute on Disability and Rehabilitation Research grant H133G050230.
Competing interests: None.
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