Statistics from Altmetric.com
Correspondence to: Professor Peter Tyrer, Department of Psychological Medicine, Imperial, St Dunstan’s Road, London W6 8RP, UK; email@example.com
Do risperidone or haloperidol reduce aggressive challenging behaviour more than placebo in people with intellectual disability?
86 adults with intellectual disability (intelligence quotient <75) and aggressive challenging behaviour (⩾2 episodes of aggressive behaviour, modified overt aggression scale (MOAS) score ⩾4 in past 7 days), but who had not received a clinical diagnosis of psychosis. Exclusions: depot or injected antipsychotics in the past 3 months, oral antipsychotics in the past week; currently sectioned under the Mental Health Act.
Ten centres in the UK and one centre in Australia; recruitment 2002–6.
Risperidone, haloperidol or placebo for 12 weeks, with the option to continue to 26 weeks. Drug dosage could be adjusted by the clinician (risperidone dose …
Source of funding: National Coordinating Centre for Health Technology Assessments.
▸Additional notes are published online only at http://ebmh.bmj.com/content/vol11/issue3
Competing interests: None.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.