Article Text

Download PDFPDF

Cognitive behavioural therapy and interpersonal therapy comparably effective for major depression

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Professor Sue Luty

Department of Psychological Medicine, Christchurch School of Medicine & Health Sciences, PO Box 4345, Christchurch, New Zealand;



Cognitive behavioural therapy (CBT) or interpersonal psychotherapy (IPT): which is more effective for depression?


177 adults (aged over 18 years) with DSM-IV non-psychotic major depression. Main exclusions: history of mania, schizophrenia, major physical illness, moderate or severe current alcohol or drug dependence, antisocial personality disorder or failure to respond to a recent (within the last year) trial of either CBT or IPT.


Recruitment from various sources including mental health out-patient clinics, psychiatric emergency services, self-referral and general practitioners between August 1998 and February 2003; treatment delivered in a university-based outpatient research unit.


CBT or IPT for up to 16 weeks. Both approaches were delivered as 50-minute weekly sessions.


Change in depression symptoms (% change in Montgomery-Asberg Depression Rating Scale (MADRS) score) between baseline and follow-up.

Patient follow-up:

89.8% of people completed adequate treatment (at least 8 sessions of weekly therapy); 100% included in intention-to-treat analyses.



Randomised controlled trial. …

View Full Text


  • Source of funding: Health Research Council of New Zealand.


  • Competing interests: None.