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van der Kolk BA, Spinazzola J, Blaustein ME, et al. A randomized clinical trial of eye movement desensitization and reprocessing (EMDR), fluoxetine, and pill placebo in the treatment of posttraumatic stress disorder: treatment effects and long-term maintenance. J Clin Psychiatry 2007;68:37–46.
METHODS
Design:
Randomised controlled trial.
Allocation:
Concealed.
Blinding:
Double blind.
Follow-up period:
Eight months (2 months’ treatment plus 6 months’ post-treatment follow-up).
Setting:
Recruitment via newspaper ads, the Internet, and from medical and mental health professionals, USA; July 2000 to July 2003.
Patients:
88 people aged 18–65 years old with current post-traumatic stress disorder (PTSD) (DSM-IV) and mixed trauma exposure at least one year before enrolment. Main exclusions: contraindication to study treatments, previous use of study treatments, Global assessment of functioning score <40, unstable medical comorbidity, psychotic or bipolar disorder, alcohol or …
Footnotes
Source of funding: National Institute of Mental Health, USA.
Footnotes
Competing interests: None.
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