Article Text

Antidepressants increase risk of suicide attempt, but not completed suicide, in people with previous suicide attempts

Statistics from

OpenUrlCrossRefPubMedWeb of Science

Q Do antidepressants decrease suicide risk in people previously hospitalised for attempted suicide?


Embedded ImageDesign:

Cohort study.

Embedded ImageFollow-up period:

Mean follow-up 3.4 years.

Embedded ImageSetting:

Finland; January 1997 to December 2003.

Embedded ImagePeople:

15 390 people (49% male; mean age 39 years) hospitalised for suicide attempt. Exclusions: psychosis or <10 years old.

Embedded ImageRisk factors:

Antidepressant use: data from the Social Insurance Institution of Finland indicated medication use. Follow-up was divided into periods of using and not using antidepressants; and the risks of attempted suicide, completed suicide and death compared during each period. Outcomes were compared for people currently on antidepressants, or had stopped, or had never taken antidepressants. Analyses were adjusted for suicide propensity score, number of antidepressant prescriptions obtained in the previous year, use of more than one antidepressant, number of severe suicide attempts requiring hospitalisation in the previous 5 years, number of suicide attempts …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.