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Q Does adherence therapy improve quality of life in people with schizophrenia?
Randomised controlled trial.
Single blind (assessors blinded).
One year (including 8-week treatment period).
Inpatient and community psychiatric services in four European cities (Amsterdam, London, Leipzig and Verona); recruitment June 2002 to October 2003.
409 adults with ICD-10 schizophrenia and evidence of clinical instability in the preceding year (change in medication, increased contact with mental health services, psychiatric hospital admission, or reported clinical instability) needing antipsychotic medication. Exclusion criteria: alcohol or drug dependence; organic brain disorder or mental handicap; receiving forensic psychiatric services.
Adherence therapy (see http://www.adherencetherapy.com): 8 weekly sessions of individual cognitive-behavioural therapy, or …
For correspondence: Dr Richard Gray, Health Services Department, Institute of Psychiatry, King’s College London, De Crespigny Park, London SE5 8AF, UK;
Source of funding: The Quality of Life and Management of Living Resources Programme of the European Union.
Competing interests: None declared.
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