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Systematic review with meta analysis.
MEDLINE, Cochrane Database, PsycINFO, and PSYNDEX (search date not stated).
Study selection and analysis:
Included studies compared pharmacotherapeutic or psychotherapeutic interventions versus control (eg, placebo or waiting list) in older adults (mean or median age ⩾60 years) with major or minor depressive or dysthymic disorder (ICD-10, DSM-III, DSM-IIIR or DSM-IV). Exclusions: combined, maintenance or collaborative treatments; studies recording insufficient data for analysis. Continuous measures were meta-analysed with Cohen’s d using a random-effects model. Odds ratios and Mantel–Haenszel effect estimates were calculated for dichotomous outcomes.
Clinician-rated or self-rated symptom severity, response, remission.
Eighty nine controlled studies, including 70 randomised controlled trials …
For correspondence: Dr Pinquart, Institute of Psychology, University of Jena, Am Steiger 3, Haus 1, 07743 Jena, Germany;
Source of funding: National Institute of Mental Health, USA.