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Phobic anxiety and depression increase the risk of ventricular arrhythmias in people with coronary artery disease

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OpenUrlAbstract/FREE Full Text

Q Are phobic anxiety and depression associated with ventricular arrhythmia?


Embedded ImageDesign:

Prospective cohort study.

Embedded ImageSetting:

Duke Medical Centre, North Carolina, USA; enrolment April 1999 to June 2002.

Embedded ImagePopulation:

940 adults (aged 29–90 years) with coronary artery disease (prior heart attack or revascularisation procedure, or ⩾75% stenosis of one coronary artery) attending hospital for diagnostic cardiac catheterisation. Exclusions: abnormal sinus rhythm at baseline; myocardial infarction or revascularisation procedure in the previous month; major non-affective psychiatric disorder; communication difficulties.

Embedded ImagePrognostic factors:

Phobic anxiety was assessed using the Crown-Crisp phobic anxiety subscale. To assess the effect of phobic anxiety as a predictor of outcome, participants in the middle of …

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  • For correspondence: Lana L Watkins, Department of Psychiatry and Behavioral Sciences, Box 3119, Duke Medical Centre, Durham, NC 27710, USA; watki017{at}

  • Source of funding: National Institutes of Health, USA.

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